Recently,with the development of pharmacochemistry,a large amount of lead compound come into sight. However, most of them are weak in druggability due to the high hydrophobic.Considering this defect,by means of typical galenic pharmacy, parts of this weakness can be solved. In addition, the delivery system of nanomedicine based on the characteristic design of oncobiology arises a wide concern.researchers strive for all kinds of nanomedicine applied for tumor-specific treatment.Neverthless,decades pass by,basic requirements for clinical use still can no be met the needs.Most importantly,most in nanomedicine prescription report which may lead to the damage of biosafety.